Welcome!

Skeptics in the Pub (SitP) exists to provide an opportunity for people who are interested in science, skepticism, rationalism, critical thinking to socialise and discuss matters of interest. Each month we invite someone to come and speak to us, and if there's someone you'd like to hear, let us know!

Follow us on Twitter at http://twitter.com/Brum_Skeptics

See also:

Birmingham Skeptics Own Web Page

SitP Birmingham page on Facebook

Birmingham Skeptics Podcast

 Other sites of note for the questioning Midlander

 Cafe Scientifique

Calendar of events at the WMAM site

Birmingham Salon

Lichfield Humanists

Birmingham Humanists

 

 

 

Henry Drysdale

When?
Wednesday, October 12 2016 at 7:30PM

Download iCalendar file
(e.g. import to Outlook or Google Calendar)

Where?

48 John Bright Street
Birmingham
B1 1BN

Who?
Henry Drysdale

What's the talk about?

 Description

For 6 weeks in late 2015, the COMPare team monitored every clinical trial published in the top 5 medical journals for “outcome switching”: when trialists report something different from what they originally said they would report. Of 67 trials assessed, 58 (87%) were found to contain discrepancies between prespecified and reported outcomes.


Outcome switching is already known to be extremely common, even in top medical journals. But COMPare went one step further: they wrote a letter to the journal for all 58 trials found to contain discrepancies; to correct the record on the individual trials, and to test the “self-correcting” properties of science.


The responses to these letters from journal editors and trial authors were unprecedented, and shed light on the reasons why this problem persists. The aim of COMPare was to fix outcome switching, through correction letters and open discussion. They never expected the levels of misunderstanding and bias at the heart of the issue.


Bio

Based at the Centre for Evidence-Based Medicine, COMPare is made up of three senior researchers, 5 graduate-entry medical students, and a programmer. The project was born when one medical student came to the department in search of a project. The idea of monitoring the outcomes in clinical trials was made possible by 4 more medical students, who were recruited to make the vast amount of analysis possible. All assessments are reviewed by senior colleagues, and decisions made at weekly team meetings. There is no specific funding for COMPare: all the students work for free, driven by the desire and opportunity to fix a broken system.


Visit the COMPare website (COMPare-trials.org) for more details about their team, methods, results and blog.

 

This is a free event, although donations to help fund Birmingham Skeptics in the Pub events are appreciated.  Seats are limited and offered on a first-come, first-served basis. If you are unable to stand for the duration of the talk let us know beforehand and we will reserve one for you.

Please fill in the form below to send us a message